Bridges of Hope
Plate
Plate 02Therapies
Status
Not specified

Therapies & Breakthroughs

Every announced breakthrough, and — the part nobody publishes — what happened to it afterwards.

What has to be decided first

What qualifies as an entry at all, what states it can be in (replicated, in trial, stalled, quietly abandoned, approved), and what signal detects that a promising line went dark.

Tracked as ticket 006-what-counts-as-a-breakthrough

What the head of an article looks like

A specimen, not an entry. It is here so the format can be reviewed before the first real article is written.

Stage of testing

?

Where the work is, taken from the trial registry. This is a fact rather than a judgement. It says nothing about whether the thing works.

Phase II

A first look at whether anything happens at all. Usually with no comparison group.

Evidence level

?

What kind of study is behind it. The level says how the question was asked, not how good the answer turned out. How much the result can carry is in the article below, with the reasoning beside it so it can be checked.

No comparison group

Treated people observed, with nobody to compare them against.

0/100

Evidence score. Computed from the level and the provenance flags beside it, not estimated.

  • from the level: 40
  • Preprint: -15
  • Industry funded: -10
  • Surrogate endpoint: -15

  • PreprintNot peer reviewed.
  • Industry fundedPaid for by the company whose product is being tested.
  • Surrogate endpointWhat was measured is a marker, not survival or symptoms.

What became of it

?

The part the press release does not have. An announced breakthrough is worth something only once somebody has checked what came of it years later.

Stalled

No new trial and no publication for years.